Molecular Genetics Core
Genetic Tools for Diabetes Discovery
The Molecular Genetics Core provides services related to the application of genetic methodologies to diabetes-related research.
Access Our Services
All customers, request services by emailing [email protected].
How We Serve Your Research Needs
- Gene edited alleles (base changes/deletions)
- Knockout alleles
- loxP-flanked alleles
- Large DNA fragment insertions targeting transgenes such as Cre and Flp recombinases or fluorescent reporters (e.g., GFP) to genes of interest
- Cost includes targeting design, testing of guide RNAs for DNA targeting, and screening of potential founders by PCR and sequence analysis. Note: cost does NOT include injection costs
- Application of CRISPR-Cas9 technology in specific genetic backgrounds is available on request, at extra cost
- Constitutive and inducible AAV viruses
- Defective pseudotyped rabies viruses for tract-tracing, including AAV helper viruses
- Under development: AAV-driven CRISPR/Cas9 reagents for gene ablation in animals; yellow fever virus for anterograde neuronal circuit tracing
Key Personnel
David P Olson, MD, PhD
David Murray Cowie M.D.
Research Professor of Pediatrics
Professor of Pediatrics
Professor of Molecular and Integrative Physiology
Medical School
Research Professor of Pediatrics
Professor of Pediatrics
Professor of Molecular and Integrative Physiology
Medical School
Qing Zhu, MD
Research Lab Specialist Associate
Contact Us
Molecular Genetics Core
North Campus Research Complex (NCRC), Building 25-3753
Email: [email protected]
