Molecular Genetics Core
Genetic Tools for Diabetes Discovery
The Molecular Genetics Core provides services related to the application of genetic methodologies to diabetes-related research.
Access Our Services
All customers, request services by emailing [email protected].
How We Serve Your Research Needs
- Gene edited alleles (base changes/deletions)
- Knockout alleles
- loxP-flanked alleles
- Large DNA fragment insertions targeting transgenes such as Cre and Flp recombinases or fluorescent reporters (e.g., GFP) to genes of interest
- Cost includes targeting design, testing of guide RNAs for DNA targeting, and screening of potential founders by PCR and sequence analysis. Note: cost does NOT include injection costs
- Application of CRISPR-Cas9 technology in specific genetic backgrounds is available on request, at extra cost
- Constitutive and inducible AAV viruses
- Defective pseudotyped rabies viruses for tract-tracing, including AAV helper viruses
- Under development: AAV-driven CRISPR/Cas9 reagents for gene ablation in animals; yellow fever virus for anterograde neuronal circuit tracing
Key Personnel
Qing Zhu, MD
Research Lab Specialist Associate
Contact Us
Molecular Genetics Core
North Campus Research Complex (NCRC), Building 25-3753
Email: [email protected]
