MDRC Research: Pilot & Feasibility

Amanda Bicket, MD, Assistant Professor, Ophthalmology and Visual Sciences, “Assessing Gait Variability in Diabetic Retinal Disease Through Wearable Technology”

David Lorberbaum, PhD, Assistant Professor, Pharmacology, “Defining the intersection of retinoic acid signaling and GATA4 during pancreas development and its impact on islet function in diabetes” (PF renewal)

Haiyan Wang, PhD, Research Investigator, School of Kinesiology, “A Novel Approach to Test the Role of the Hexosamine Biosynthetic Pathway in the Reversal of the Postexercise Increase in Insulin-Stimulated Glucose Uptake by Skeletal Muscle”

Cristina Espinosa-Diez, PhD, Assistant Professor, Center of Molecular Medicine and Genetics, Wayne State University, “Role of LncRNAs in endothelial dysfunction in diabetic kidney disease”

Charlie Fehl, PhD, Assistant Professor, Chemistry, Wayne State University, “Targeting aberrant O-linked N-acetylglucosamine (O-GlcNAc) glycosylation in prediabetic insulin resistance”

Joseph Patterson, PhD, Assistant Professor, Translational Neuroscience, Michigan State University, “Assessment of the effects of insulin resistance and hyperglycemia on synucleinopathy progression”

David Lorberbaum, PhD, Assistant Professor, Pharmacology, “Defining the intersection of retinoic acid signaling and GATA4 during pancreas development and its impact on islet function in diabetes”

Shiying Li, PhD, Assistant Research Scientist, Internal Medicine - Gastroenterology, “Methylglyxoal modulates sodium channels in gastric smooth muscle cells underlying the impaired gastric accommodation in Diabetes Gastroparesis”

Nicholas Ferrell, PhD, Assistant Professor, Internal Medicine - Nephrology, Ohio State University, “Engineered Extracellular Vesicles to Attenuate Oxidative Stress and Inflammation in Diabetes”

Hanna Hoffman, PhD, Assistant Professor, Animal Science, Michigan State University, “Role of zinc in uterine contractile malfunction in pregestational diabetes”

Shahnawaz Imam, DVM, PhD, Assistant Professor, University of Toledo, “Pancreatic islets rescue in Type 1 Diabetes using immunomodulators”

Stephanie Eid, PhD, Research Assistant Professor, Neurology, “Schwann cell-derived extracellular vesicles in prediabetic neuropathy: Role in nerve insulin signaling and function”

Maria Cristina Foss De Freitas, MD, PhD, Research Investigator, Internal Medicine, “A truncating mutation of EBF2 disrupts adipocyte differentiation in lipodystrophy: an example of a discovery from a clinical translational pipeline”

Aitor Aguirre, PhD, Assistant Professor, Biomedical Engineering, Michigan State University, “A human heart organoid model to study maternal-diabetes induced cardiac embryopathies”

Geoffroy Laumet, PhD, Assistant Professor, Physiology, Michigan State University, “Central Neurotensin in Alleviating Comorbid Obesity and Pain”

Kristy Townsend, MD, Associate Professor, Neurological Surgery, Ohio State University, “Determining the functional impacts and mechanistic actions of the sensory neuropeptide calcitonin gene related peptide (CGRP) in adipose tissue”

Ciria C. Hernandez, MD, PhD, Assistant Research Scientist, Life Sciences Institute, “Novel Blockers of β-Cell KCa Channels and Insulin Secretion”

Jennifer Schaub, MD, Assistant Professor, Internal Medicine, “A systems biology approach to identify patients with Diabetic Kidney Disease that may benefit from novel prolyl hydroxylase inhibitors”

Colleen Buggs-Saxton, MD, PhD, Associate Professor, Pediatrics, Wayne State University, “Evaluating the utility of a wireless-enabled “smart” Insulin Pen to improve glycemic control in pediatric type 1 diabetes”

Marianna Sadagurski, PhD, Assistant Professor, Biological Sciences, Wayne State University, “Volatile organic compounds exposure and predisposition to metabolic disease”

Ken Inoki, MD, PhD, Associate Professor, Life Sciences Institute, Molecular and Integrative Physiology, University of Michigan, “Role of lysosomal cholesterol sensing machinery and obesity”

James Moon, PhD, John Gideon Searle Associate Professor in the Department of Pharmaceutical Sciences, Department of Biomedical Engineering, and Graduate Program in Immunology, University of Michigan, “New approach for immune modulation against T1D”

Rodica Pop-Busui, MD, PhD, Professor, Internal Medicine; Eva Feldman, MD, PhD, Russell N. DeJong Professor of Neurology; Salim Hayek, MD, Assistant Professor, Internal Medicine; Subramaniam Pennathur, MD, Professor of Medicine and Molecular and Integrative Physiology; and Matthias Kretzler, MD, Warner-Lambert/Parke-Davis Professor of Medicine, “Incidence and predictors of acute and chronic diabetes complications in patients with severe COVID-19”

• Awardee of the Caswell Diabetes Institute COVID-19 and Metabolic Disease Grant Program

Terrence Wong, MD, PhD, Assistant Professor, Hematology and Oncology and Jacob Kitzman, PhD, Assistant Professor, Human Genetics, “Impact of clonal hematopoiesis on COVID-19 morbidity and mortality”

• Awardee of the Caswell Diabetes Institute COVID-19 and Metabolic Disease Grant Program

Paul Burghardt, PhD, Associate Professor, Nutrition and Food Science, Wayne State University, “The role of IL-18 and excitatory/inhibitory imbalances of top-down/bottom-up processes to food cues as a predictor of successful maintenance of weight loss”

Alexander W. Johnson, PhD, Associate Professor, Psychology, Michigan State University, “Lateral hypothalamic control over cephalic insulin release”

Mehboob Hussain, MD, Professor, Internal Medicine and Lonnie Shea, PhD, Professor, Biomedical Engineering, “Next generation hESC-derived Beta-cell engineering”

• Awardee of the William and Delores Brehm Research Award in Type 1 Diabetes Mellitus

Kara Mizokami-Stout, MD, Clinical Lecturer, Internal Medicine, “Hybrid closed loop adoption and patterns of use in veterans with type 1 diabetes mellitus”

• Awardee of the William and Delores Brehm Research Award in Type 1 Diabetes Mellitus

Lucia Russo, PhD, Research Investigator, Pediatrics-Pulmonary Medicine, University of Michigan, “Study of cholesterol 25-hydroxylase in the regulation of adipose tissue inflammation using human approaches”

Scott Soleimanpour, MD, Assistant Professor, Internal Medicine, “Investigating structure-function relationships of disease variants encoded by the type 1 diabetes gene Clec16a”

• Awardee of the William and Delores Brehm Research Award in Type 1 Diabetes Mellitus

Deqiang Zhang, PhD, Research Investigator, Molecular and Integrative Physiology, “ChREBP acetylation by CLOCK in non-alcoholic fatty liver disease”

Emilio Mottillo, PhD, Assistant Scientist, Hypertension and Vascular Research Division, Henry Ford Health System, “Piloting the ABHD5/PNPLA3 metabolon in response to endogenous lipid ligands”

Hyunbae Kim, PhD, Research Scientist, Center for Molecular Medicine and Genetics, Wayne State University, “Role of stress-induced miRNA decay in metabolic disorder”

Eric Buras, MD, PhD, Clinical Lecturer, Internal Medicine, University of Michigan, “Fibro-adipogenic remodeling of the diaphragm in obesity hypoventilation syndrome”

Christian Burgess, PhD, Assistant Professor, Molecular & Integrative Physiology; Research Assistant Professor, Molecular & Behavioral Neuroscience Institute, University of Michigan, “Investigating the relationship between lateral hypothalamic peptide release and energy balance”

Laura Saslow, PhD, Assistant Professor, School of Nursing, Department of Health Behavior & Biological Sciences, University of Michigan, “Diet and lifestyle management for obese women with polycystic ovary syndrome”

Charles Chung, PhD, Assistant Professor, Physiology, Wayne State University, “Does insulin signaling regulate cardiac stiffness via regulation of titin splicing?”

Gina Leinninger, PhD, Assistant Professor, Physiology, Michigan State University, “Contribution of orexin-DLK1 neurons to body weight and behavior”

David Bridges, PhD, Assistant Professor, Nutritional Sciences, “The role of adipose tissue in obesity-associated glucocorticoid responses”

Isin Cakir, PhD, Research Investigator, Life Sciences Institute, “Reversal of diet-induced obesity with histone deacetylase 6 inhibitors”

Ulrike Klueh, PhD, Associate Professor, Biomedical Engineering, Wayne State University, “Development of blood biomarkers for clinical management of diabetic foot ulcers”

Suresh Palaniyandi, PhD, Assistant Scientist, Internal Medicine - Hypertension and Vascular Research Division, Henry Ford Health System, “Role for ALDH2 in endothelial cell energy metabolism in diabetic cardiomyopathy: An iPSC approach”

Jonathan Flak, PhD, Research Investigator, Internal Medicine, University of Michigan “Uncovering the neurocircuitry that drive counterregulation downstream from the VMN”

Carol F. Elias, PhD, Associate Professor, Molecular and Integrative Physiology “Cellular and molecular basis of diabetes-induced placental dysfunction”

Robert Wessells, PhD, Assistant Professor, Physiology, Wayne State University “Cardiac lipolysis in Drosophila is controlled by the ABHD5 homolog bremse (CG1882)”

Xiangmin Zhang, MD, PhD, Assistant Professor of Research, Pharmaceutical Sciences, Wayne State University “Recombinant attenuated bacteria as drug to initiate insulin synthesis in vivo”

Kevin Atkins, MD, PhD, Assistant Research Scientist, Internal Medicine-Nephrology, University of Michigan “The role of GLUT4 on the development of vasculopathy in diabetes”

Marianna Sadagurski, PhD, Assistant Research Scientist, Internal Medicine, Geriatrics & Palliative Medicine University of Michigan “Role of growth hormone receptor (GHR) in nutrient-sensing leptin receptor expressing neurons (LEPR-B) in physiology and neuronal function”

Renny Franceschi, PhD, Professor, Periodontics & Oral Medicine, School of Dentistry, University of Michigan “Discoidin receptor 2 and adiponectin in energy and mineral homeostasis; relationship to type 2 diabetes”

Brigid Gregg, MD, Assistant Professor, Pediatric Endocrinology, Department of Pediatrics, University of Michigan “Understanding the role of metformin during lactation in programming of offspring weight and glucose homeostasis”

Wei Perng, PhD, MPH, Department of Nutritional Sciences, SPH, University of Michigan “A prospective study of metabolomics patterns and glycemia in U.S. and Mexican Children”

Kyle Burghardt, PharmD, Assistant Professor, College of Pharmacy and Health Sciences, Wayne State University “Insulin resistance induced by antipsychotic medication in the absence of weight gain: impact of skeletal muscle epigenetic and protein mechanisms”

Jennifer Hill, PhD, Assistant Professor, Physiology and Pharmacology, University of Toledo “Intergenerational obesity resulting from lactational impairment”

Alexander Johnson, PhD, Assistant Professor, Department of Psychology, Michigan State University “Modulation of predictive regulation via chemogenetic and optogenetic control of Melanin Concentrating Hormone”

Craig Harris, PhD, Professor of Toxicology, Environmental Health Sciences, University of Michigan “Fetal programming of oxidative stress and insulin resistance”

Elizabeth Speliotes, MD, PhD, MPH, Assistant Professor, Internal Medicine-Gastroenterology, University of Michigan “Metabolic studies on Lypla1 mutant mice”

Jun Wu, PhD, Research Investigator, Neurology, University of Michigan “The role of activation of RAGE by AGEs in diabetes-induced neuropathic pain”

Ren Zhang, MD, PhD, Assistant Professor, Center for Molecular Medicine & Genetics, Wayne State University “Examination of therapeutic potentials of lipasin monoclonal antibodies and the ChREBP-mediated transcriptional regulation”

Jian Wang, MD PhD, Assistant Professor, Pathology, Wayne State University “Regulation of glycine metabolism is diabetes”

Paula Goforth, PhD, Assistant Research Scientist, Pharmacology, University of Michigan, “Chronic regulation of lateral hypothalamic circuits by leptin”

Jennifer W. Hill, PhD, Assistant Professor, Physiology and Pharmacology, University of Toledo, “Inflammatory processes driving insulin resistance in polycystic ovary syndrome”

Marianna Sadagurski, PhD, Assistant Research Scientist, Internal Medicine, University of Michigan, “Hypothalamic inflammation and energy homeostasis in long-lived mice models and its impact on whole body metabolism and metabolic signaling”

Dawn P Misra, PhD, MHS, Professor, Family Medicine and Public Health Science, Wayne State University, “Epigenetic mediators of the obese intrauterine environment”

Xin Tong, MD, PhD, Research Investigator, University of Michigan, “Regulation of lipid metabolism by DDB1-CUL4A E3 ligase in liver steatosis”

Jun Li, PhD, Assistant Professor, Human Genetics, University of Michigan, “Genetic analysis of a rat model of aerobic capacity and diabetes risk”

Atta Ahmad, PhD, Research Investigator, Life Sciences Institute, University of Michigan, “Examining the role of chaperones in insulin quality control and its relation to type II diabetes”

Diane M. Robins, PhD, Professor, Human Genetics, University of Michigan, “KRAB-ZFPs as genetic modifiers of sex-dependent metabolic disease”

Anuska V. Andjelkovic-Zochowska, MD, PhD, University of Michigan, Assistant Professor, Pathology, “Blood brain barrier dysfunction in diabetes: The role of miRNA 126 in regulation of blood brain barrier integrity”

Gina M. Leinninger, PhD, Assistant Professor, Physiology, Michigan State University, “Role of lateral hypothalamic neurotensin signaling in energy balance and obesity”

Xuequn Chen, PhD, Assistant Professor, Physiology, Wayne State University, “Quantitative proteomic analysis of altered ER homeostasis in pancreatic beta cells”

Tae-Hwa Chun, MD, PhD, Assistant Professor, Internal Medicine-MEND, “Peri-adipocyte fibrosis and adipocyte dysfunction in diabetes”

James Wrobel, DPM, Clinical Associate Professor, Internal Medicine-MEND, “Multi-material, layer, and density approach to shear and pressure reduction in the treatment and prevention of diabetes-related foot ulcer”

Jeffrey B. Hodgin, MD, PhD, Assistant Professor of Pathology, “Deep sequencing of the podocyte transcriptome in diabetic and hypertensive mice”

David S. Olson, MD, PhD, Clinical Instructor, Pediatrics, Pediatrics and Communicable Diseases, “Translational profiling of neurons involved in feeding”

Deneen Wellik, PhD, Associate Professor of Internal Medicine and Cell and Developmental Biology, “The role of Hox6 genes in the pancreatic niche”

Menq-Jer Lee, PhD, Associate Professor, Pathology, Wayne State University, “Role of lipolysis activated autocrine sphingosine-1-phosphate signaling in adipocyte function”

Roseanne Armitage, PhD, Professor of Psychiatry, “Measurement of sleep physiology in obese and type 2 diabetic patients”

Markus Bitzer, MD, Assistant Professor, Department of Internal Medicine, Division of Nephrology, “The role of microRNA-21 in diabetic nephropathy”

Christopher Krebs, PhD, Research Investigator, Department of Internal Medicine, Division of Human Genetics, “Distinguishing the mouse RsI genes as genetic modifiers of hepatic insulin sensitivity”

David Lombard, MD, PhD, Assistant Professor, Department of Pathology, Research Assistant Professor, Institute of Gerontology, “Novel mechanisms of pyruvate dehydrogenase complex regulation”

Lei Yin, PhD, Assistant Professor, Department of Molecular and Integrative Physiology, “Circadian regulation of AMPK signaling and glucose metabolism by the transcription repressor E4BP4 “

Munmum Chattopadhyay, PhD, Research Investigator, Department of Neurology, “Role of neuroinflammation in painful neuropathy in Type 2 diabetes”

Alla Karnovsky, PhD, Research Investigator, Center for Computational Medicine & Bioinformatics. “Development and application of bioinformatics tools for metabolomics and diabetes”

Joyce Lee, MD, MPH, Assistant Professor, Department of Pediatrics, Division of Pediatric Endocrinology “The Pediatric Diabetes Consortium (PDC): Improving care in children with type 1 diabetes through collaborative research”

Sung Kyun Park, ScD, MPH, Assistant Professor, Department of Environmental Health Sciences, “Bisphenol-A, epigenetics and type-2 diabetes”

Scott Pletcher, PhD, Associate Professor, Department of Molecular and Integrative Physiology and Geriatrics, “Identification of novel mechanisms of metabolic homeostasis in Drosophila”

Bin Xu, PhD, Research Assistant Professor, Department of Internal Medicine, “Novel function of the RNA activator SRA in adipogenesis”

Peter Dempsey, PhD, Associate Professor, Pediatric Gastroenterology, "Role of ErbB4 receptor signaling in the Central Regulation of Energy Metabolism"

Carey Lumeng, MD, PhD, Assistant Professor, Pediatrics, “Depot-specific differences in adipose tissue macrophages “Michigan macrophages in adipose tissue”

Sandeep Pandit, PhD, Professor, Internal Medicine-Cardiology, “Arrhythmogenesis in type-1 diabetes”

Rodica Pop-Busui, MD, PhD, Assistant Professor, Internal Medicine, “Stress induced hyperglycemia: A predictor of long-term glucose abnormalities in patients undergoing cardiovascular surgery?”

Bhumsoo Kim, PhD, Research Assistant Professor, Neurology, “Animal models of increased Alzheimer's disease progression with diabetic background”

Maria Dolors Sans Gili, PhD, Assistant Professor, Molecular and Integrative Physiology, “Insulin, diabetes and the regulation of pancreatic digestive enzymes”

Ming Liu, MD, PhD, Research Investigator, Internal Medicine, “Dominant negative effects of misfolded proinsulin in pancreatic beta cells”

Ayyalusamy Ramamoorthy, PhD, Associate Professor of Chemistry, “Solid-state NMR studies on human islet amyloid polypeptide and its role in beta-cell membrane disruption”

Allison Rosen, MD, MPH, ScD, Assistant Professor, Internal Medicine and Health Management and Policy Clinical Director, Center for Value-Based Insurance Design, “Trends in the cost of diabetes care in the United States: 1996-2004”

Patrick J. Hu, MD, PhD, Assistant Professor, Internal Medicine, “A novel endocrine pathway regulating insulin-like signaling in C. elegans”

Jiandie Lin, PhD, Assistant Professor of Cell & Developmental Biology and Life Sciences Institute, “Genome-wide analysis of transcription factors in the regulation of mitochondrial biogenesis by PGC-1α”

Julie C. Lumeng, MD, Assistant Research Scientist and Assistant Professor of Pediatrics, “Factors impacting maternal beliefs and feeding practices in mothers of low-income African American Preschoolers”

Heike Muenzberg, PhD, Research Investigator, Internal Medicine, “Leptin signaling in the DMH and its role in feeding circuits”

Subramaniam Pennathur, MD, Assistant Professor of Medicine, “Molecular mechanisms of pancreatic β-cell failure in vivo”

Alison Affinati, MD, PhD, Assistant Professor, Internal Medicine - MEND and Joanna Spencer-Segal, MD, PhD, Assistant Professor, Internal Medicine - MEND, “Identifying the neural circuits that underlie hypoglycemia-associated autonomic failure" (DISP renewal)

Markus Bitzer, MD, Clinical Professor, Internal Medicine-Nephrology and Wenjun Ju, PhD, Research Scientist, Internal Medicine-Nephrology, “TGFBI mediates renal epithelial detachment in diabetic kidney disease”

Alison Affinati, MD, PhD, Assistant Professor, Internal Medicine - MEND and Joanna Spencer-Segal, MD, PhD, Assistant Professor, Internal Medicine - MEND, “Identifying the neural circuits that underlie hypoglycemia-associated autonomic failure”

Anuska Andjelkovic-Zochowski, MD, Professor, Pathology and Carol Elias, PhD, Professor, Molecular & Integrative Physiology, “Obesity-induced blood-brain-barrier dysfunction during postnatal development”

Yu Kuei Lin, MD, Assistant Professor, Internal Medicine - MEND and Melissa DeJonckheere, PhD, Assistant Professor, Family Medicine, “Determining Barriers to Optimal Hypoglycemia Self-management in Adults with Type 1 Diabetes Using Advance Diabetes Technologies”

Manjunath (Amit) Pai, PharmD, Professor and Chair, Clinical Pharmacy and Amy Rothberg, MD, PhD, Clinical Professor, Internal Medicine - MEND, “Engineering a Type 2 Diabetes Precision Drug Dosing Model”

Monica Dus, PhD, Assistant Professor, Molecular, Cellular, and Developmental Biology, Life Sciences Institute and Carrie Ferrario, PhD, Professor, Department of Pharmacology, University of Michigan “Reprogramming of dopamine neuron identity with diet-induced obesity”

Jacob M. Haus, MS, PhD, Associate Professor, School of Kinesiology at the University of Michigan; Michael Munson DPM, Assistant Professor, Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan; and Crystal Holmes DPM, Clinical Associate Professor, Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, “Non-weight bearing exercise for accelerated healing of diabetic foot ulcers”

Ormond MacDougald, PhD, John A Faulkner Collegiate Professor of Physiology, Professor of Molecular and Integrative Physiology and Professor of Internal Medicine, University of Michigan, and Elif Oral, MD, Professor of Internal Medicine, University of Michigan, “Mechanisms by which lamin A/C deficiency causes loss of adipose tissues”

Mehboob Hussain, MD, Professor, Internal Medicine - MEND, University of Michigan; Sunitha Nagrath, PhD, Associate Professor, Chemical Engineering, University of Michigan; and Deepak Nagrath, PhD, Associate Professor, Biomedical Engineering, University of Michigan, “In vivo ß-cell specific exosome identification and characterization in diabetes mellitus”

Jason S. Knight, MD, PhD, Assistant Professor, Internal Medicine-Rheumatology, University of Michigan, and Subramaniam Pennathur, MD, Norman Radin Professor of Nephrology, Professor, Internal Medicine and Molecular & Integrative Physiology, University of Michigan, “Role of neutrophil extracellular traps in diabetic cardiovascular disease”

Bethany B. Moore, PhD, Galen B. Toews MD Collegiate Professor of Pulmonary & Critical Care Medicine, Professor, Internal Medicine and Microbiology & Immunology, and Director, Doctoral Program in Immunology, University of Michigan, and Katherine A. Gallagher, MD, John R. Pfeifer Collegiate Professor of Vascular Surgery, Associate Professor, Surgery, “Prostaglandin E2 synthesis alters macrophage function to promote inflammation and impair diabetic wound healing”

Robert O’Rourke, MD, Associate Professor, Surgery, and Lonnie Shea, PhD, Professor and Chair, Department of Biomedical Engineering, “Engineered adipose tissue-bioscaffolds as a therapeutic tool for type 2 diabetes”.

Amy Rothberg, MD, Associate Professor, Internal Medicine, and Andrew Schrepf, PhD, Research Investigator, Anesthesiology, “The impact of calorie restriction and weight loss on inflammation and centralized pain in individuals at risk for diabetes”.

Jennifer Harder, MD, Clinical Assistant Professor, Internal Medicine-Nephrology, Cristina Cebrian-Ligero, PhD, Clinical Lecturer, Internal Medicine-Gastroenterology, and Edgar Otto, PhD, Research Assistant Professor, Internal Medicine-Nephrology “Modeling diabetic kidney disease using kidney organoids generated from human iPSC”.

Jiandie Lin, PhD, Associate Professor, Cell & Developmental Biology, Life Sciences Institute, Katsuo Kurabayashi, PhD, Professor, Mechanical Engineering and Electrical Engineering, and Jun Li, PhD, Associate Professor, Human Genetics, “Elucidating the landscape of liver cell heterogeneity in normal and insulin resistant states by single cell RNA sequencing”.

Tae-Hwa Chun, MD, Internal Medicine-Metabolism, Endocrinology, and Diabetes, University of Michigan and Shuichi Takayama, PhD, Biomedical Engineering, College of Engineering, University of Michigan, “Developing human adipose tissue on-a-chip (Fat Chip)”.

Jun Hee Lee, PhD, Assistant Professor, Molecular and Integrative Physiology and Uhn-Soo Cho, PhD, Assistant Professor, Biologic Chemistry, “Biochemical basis for Sestrin2 in metabolism”. Jointly funded by the MDRC and the Michigan Comprehensive Diabetes Center (MCDC).

Brian Callaghan, MD, Assistant Professor, Neurology and Justin Dimick, MD, MPH, Associate Professor, Surgery, “The association between the metabolic syndrome and neurologic outcomes in a bariatric surgery population.”

Steven R Buchman, MD, M Haskell Newman Collegiate Professor of Plastic Surgery, Karl J Jepsen, PhD, Glacy Family Scholar, Professor, Associate Chair for Research, Orthopaedic Surgery, and Ernestina Schipani, MD, PhD, Professor, Endocrinology, “Remediating diabetes-impaired bone fracture with Deferoxamine”. Jointly funded by the MDRC and the Michigan Comprehensive Diabetes Center (MCDC).

Blake Roessler, MD, Professor of Internal Medicine - Rheumatology, Crystal Holmes, D.P.M., Clinical Assistant Professor, Internal Medicine - Metabolism, Endocrinology and Diabetes, and Bin Nan, PhD, Professor, Biostatistics, “Point-of-care bone composition measurements for early-stage detection of osteomyelitis in the diabetic foot”. Jointly funded by the MDRC and the Michigan Comprehensive Diabetes Center (MCDC).

Steven K. Lundy, PhD, Research Assistant Professor, Department of Internal Medicine, and Massimo T Pietropaolo, MD, Professor of Internal Medicine, Pediatrics and Communicable Diseases, and Microbiology and Immunology, “Targeting killer and regulatory B lymphocyte function in IDDM”

Joshua D Stein, MD, Assistant Professor of Ophthalmology and Visual Sciences, and David W. Hutton, PhD, John G. Searle Assistant Professor of Health Management and Policy, School of Public Health and Assistant Professor of Industrial Operations, College of Engineering, “Assessing the cost effectiveness of different interventions for clinically significant diabetes macular edema”

Steve Lentz, PhD, Research Assistant Professor, Department of Internal Medicine, Division of MEND and Roni M Shtein, MD, Assistant Professor, Department of Ophthalmology, “In vivo corneal confocal microscopy for non-invasive assessment of diabetic peripheral neuropathy”

Amy Rothberg, MD, Clinical Assistant Professor, Department of Internal Medicine, Division of MEND and Jon-Kar Zubieta, MD, PhD, Phil F. Jenkins Research Professor of Depression, Professor of Psychiatry and Radiology and Research Professor, Molecular and Behavioral Neuroscience Institute, “Neurohormonal & behavioral correlates of obesity”

Eva L Feldman, MD, PhD, DeJong Professor of Neurology and Matthias Kretzler, MD, Associate Professor, Internal Medicine, and Hosagrahar V. Jagadish, PhD, Collegiate Professor of Electrical Engineering and Computer Science, “Biomarkers of diabetic microvascular complications: A bioinformatics approach to human samples”

Catherine Kim MD, MPH, Assistant Professor, Department of Internal Medicine and Obstetrics and Gynecology and Caroline Richardson, MD, Assistant Professor, Department of Family Medicine, “Pedometers in gestational diabetes”

Meng Hee Tan, MD, Clinical Professor, Internal Medicine, and David Hanauer, MD, MS, Clinical Professor, Department of Pediatrics and Communicable Diseases, “Creating a diabetes research registry to enhance recruitment of patients in clinical trials and studies at University of Michigan”

Elif Oral, MD, Assistant Professor, Internal Medicine and John D. Birkmeyer, MD, Professor, General Surgery, “Effect of dietary macrocomposition on non-alcoholic fatty liver disease in bariatric surgery candidates.” Jointly funded by the MDRC, the Michigan Comprehensive Diabetes Center (MCDC) and the Michigan Institute for Clinical and Health Research (MICHR).

Annette Chang, MD, Internal Medicine, Metabolism, Endocrinology & Diabetes and Michael Kilbourn, PhD, Radiology, “Evaluation of human pancreatic B-cell mass with [11C] dihydrotetrabenazine (DTBZ) Radioligand”

Martin G Myers, MD, PhD, Internal Medicine, Metabolism, Endocrinology & Diabetes, and Robert Thompson, PhD, Psychiatry, were awarded the MCDC/MDRC DISP award for, “Genomic analysis of novel leptin-regulated neural metabolic pathways.”