view from above of two researchers working on medical machinery

Surgery Research Areas

Department of Surgery researchers cover a lot of ground — from finding treatments to vexing diseases like pancreatic and lung cancer, to improving the organ transplantation process, to optimizing the way healthcare is delivered, to better understanding injuries.

Explore some of our department’s strengths in basic science, clinical and outcomes research.

Department of Surgery Research Strengths

Department research into cancer and tumor biology begins at the level of basic science, using novel methods to understand the proteins and signaling pathways of cancers, and extends into early clinical trials for target drugs.

Department of Surgery faculty play key roles in statewide quality collaboratives and in the University of Michigan’s Institute for Healthcare Policy & Innovation. Research focuses on understanding the impacts of state and national healthcare policy, and on studying long-term patient outcomes following surgery.

By leveraging the body’s building blocks of nerve and bone, we’re creating new treatments for patients with congenital anomalies or injuries resulting from trauma or disease. For patients who’ve lost a limb, we’re working to develop a prototype of a regenerative peripheral nerve interface that would one day allow for control of prosthetic devices.

The Department of Surgery faculty members explore a wide range of neonatal and pediatric conditions in their research efforts, reflecting the breadth of their expertise. This research seeks to improve the lives of our youngest patients.

Disorders of the metabolic system pose one of the greatest threats to human health in part because we have few effective treatments. Researchers in the Department of Surgery aim to change that by studying the molecular mechanisms of dysfunctional metabolism in order to develop new interventions for diabetes and obesity.

Our surgeon scientists are investigating new approaches to train surgeons and surgeon educators and optimize surgical training programs. We are seeking to advance surgical education research and innovation.

By teaching and modeling entrepreneurship, Department of Surgery faculty advance the development and commercialization of new treatments, new medical devices, and new ideas for the delivery of care.

From studying crash test data to developing novel treatments for severe burns, our trauma and critical care researchers bring a multidisciplinary perspective to their work, with the goal of improving trauma survivors’ quality of life and reducing the societal burden of severe injuries.

With more than a dozen dedicated faculty, our vascular research program is one of the largest of its kind and covers a broad scope of interests — including venous thrombosis, vascular inflammation, thrombus resolution, traumatic injury, nephropathy, abdominal aneurysms, and image-based modeling of hemodynamics.

Group of doctors with a patient

Support Surgery

Your contribution helps us research medical breakthroughs, make medicine more inclusive and train the next generation of surgical leaders.

Make a gift

Featured News & Stories

See all news
doctor in white coat with heart model in hand in hallway looking down
Health Lab

How a temporary heart pump can support high risk cardiac surgery

A cardiac surgeon from Michigan Medicine offers helpful details on Impella devices.
Man on the left in a hospital bed with his thumb up. Man on the right is standing next to a motorcycle wearing a suit and a helmet.
Health Lab

Texas man walking on ‘new legs’ after complex vascular procedures

A Texas man walks five miles daily on “new legs” after undergoing a minimally invasive vascular procedure at University of Michigan to restore blood flow to blocked vessels.
couple with 3 dogs on porch smiling
Health Lab

Receiving personalized treatment for a rare neuroendocrine tumor

Danielle Schuldt was diagnosed with a rare endocrine tumor and underwent surgery as part of her treatment. She now undergoes regular surveillance to monitor for cancer recurrence.
Black and white cutout of Moses Gunn in a conference ballroom.
Department News

2026 Moses Gunn Research Conference Highlights

Highlights from the Michigan Medicine Department of Surgery's 37th annual Moses Gunn Research Conference.
UMich Med Mosaic on blue background with colorful geometric shapes
UMich Med Mosaic

Beyond the White Coat: Finding Your Voice at the Patient’s Bedside

In this episode of UMich Med Mosaic, host Mackenzie Kay speaks with MD students Josh Chen and Gabriel Culian about what it feels like to step onto the hospital wards for the first time. They reflect on their earliest patient encounters, the transition from standardized patients to real clinical settings, and the role medical students play in building trust, explaining care plans and supporting patients and families. They also discuss witnessing serious illness, grief and life-changing conversations, while exploring how early clinical experiences shape confidence, empathy and the kind of physicians they hope to become.
A group of people standing on a lecture hall stage in business attire. A slide behind them reads "Finding your path in surgical innovation."
Department News

Highlights from the 2026 Reed O. Dingman Research Symposium

Learn about the Section of Plastic Surgery's 36th Reed O. Dingman Research Symposium.