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Nephrology Basic Science Research

The U-M Medical School Department of Internal Medicine Division of Nephrology and its collaborators have made significant strides in multiple basic science areas. Our strengths in these evolving areas have advanced the field of kidney disease research, leading to improvements in treatment and management options.

Areas of Interest

  • Podocyte biology
  • Molecular genetics of cystic disease and glomerulopathies
  • Acute tubular epithelial cell injury
  • Epithelial cell biology
  • Signal transduction
  • Lipid/phospholipase biochemistry and function
  • Kidney development
  • Smooth muscle biology and glucose transporters
  • Biomedical engineering

Faculty Affiliations & Research Collaborations

Several of our faculty members have joint appointments in or close research relationships with the below divisions, departments, and centers:

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Excellence in Basic Science Research

Our division proudly holds four consecutive five-year grants for the George M. O'Brien Michigan Kidney Translational Core Center, one of only eight such centers in the entire United States.

Explore George M. O'Brien Michigan Kidney Translational Core Center

Basic Science Research Faculty

portrait of Farsad Afshinnia

Farsad Afshinnia, MD MS

Clinical Associate Professor of Internal Medicine
Medical School
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Frank C Brosius III

Professor Emeritus of Internal Medicine
Medical School
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Puneet Garg, MD, FASN

Clinical Associate Professor of Internal Medicine
Medical School
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Jennifer Harder, MD

Clinical Associate Professor of Internal Medicine
Medical School
H D. Humes

H D Humes

Professor of Internal Medicine
Medical School
Kretzler

Matthias Kretzler, MD

Warner-Lambert/Parke-Davis Professor of Medicine
Professor of Internal Medicine and Research Professor
Computational Medicine and Bioinformatics
Medical School
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Benjamin L Margolis

Professor Emeritus of Internal Medicine
Medical School
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Laura Heyns Mariani, MD, MSCE

Associate Professor of Internal Medicine
Associate Chair, Department of Internal Medicine
Assistant Clerkship Director and Associate Fellowship Director - Nephrology
Medical School
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ANNA VACHAPARAMPIL MATHEW, MBBS

Clinical Associate Professor of Internal Medicine
Medical School
Sanjeevkumar R. Patel

Sanjeevkumar Patel, MD

Clinical Associate Professor of Internal Medicine
Clinical Assistant Professor of Urology and Director of Canton Dialysis Unit
Director Medical Kidney Stone Prevention Program
Canton Medical School
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Subramaniam Pennathur, MD

Norman Radin Professor of Nephrology
Professor of Internal Medicine
Professor of Molecular and Integrative Physiology and Section Head
Division of Nephrology
Medical School
James shayman

James A Shayman

Agnes C and Frank D McKay Professor
Professor of Pharmacology
Professor of Internal Medicine
Medical School
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Joel M Weinberg

Professor Emeritus of Internal Medicine
Medical School
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William F Weitzel III

Clinical Professor of Internal Medicine
Medical School
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Roger C Wiggins

Professor Emeritus of Internal Medicine
Medical School